Orotic acid is a biochemical substance made by all living cells. The mineral salts of orotic acid, called orotates, are used by plants and animals to form RNA and DNA. Perhaps the biggest proponent in the use of orotates was Dr. Hans Nieper, a German physician whose treatments were denounced by many American physicians. Nieper believed orotates were far superior in their ability to carry molecules across cell membranes, producing higher concentrations of minerals in the cell.
Dr. Nieper used orotates as treatments for many conditions. During his lifetime, Dr. Nieper was often ignored and criticized for his use of oratates. Recent research, however, has confirmed that for certain conditions, minerals bound to oratic acid are not only beneficial, but may be superior in their bioavailability and effectiveness.
Magnesium orotate is a mineral salt that is normally found in lesser amounts in all living things.
Magnesium is essential for the proper functioning of the brain, nerves, and muscles. It acts as a smooth muscle relaxant, promotes healthy glucose metabolism, and acts as a cofactor to enzymes in many biochemical reactions.1
It is essential for cellular energy production, nerve conduction, cardiac function, bone mineralization, and muscle relaxation. Magnesium may be beneficial in reducing occasional anxiety, promoting sleep, and decreasing muscle tension and occasional pain.
A 1998 study showed that triathletes who supplemented with magnesium orotate had improved glucose utilization and a reduced stress response without affecting competitive potential. This translated into improved swimming, cycling, and running times in the magnesium orotate group compared with the controls.2 Competitive athletes have also used magnesium orotate to improve endurance.
Many studies have been performed examining the role of magnesium orotate in cardiovascular health. Magnesium orotate has been shown to improve endothelial function, and exercise tolerance, studies have shown favorable effects of oral magnesium orotate to left ventricular function and exercise tolerance,4 as well as increasing survival rate and improving clinical symptoms and patient’s quality of life 3.
It is believed that magnesium orotate improves the energy status of heart muscle by stimulating the synthesis of glycogen and ATP.5
Dr. Carolyn Dean, author of “The Magnesium Miracle,” asserts that changes in our diets and the way in which food is processed have left many of us with deficient levels of the nutrient magnesium. Magnesium orotate is one compound that has been used effectively to treat magnesium deficiency and its associated symptoms. In magnesium orotate, magnesium is bound to oratic acid. the mineral is absorbed very efficiently by your body. Magnesium orotate can be used to improve sleep, as it inhibits some “stress” hormones like adrenalin. Magnesium orotate supports good hydration of your body by helping to regulate the flow of sodium and potassium through your cells.
“Magnesium deficiency is one of the most underrated minerals, but it’s involved in literally hundreds of your body’s functions. Pay attention to it, and your body will thank you.” According to author: Alexandra Whiitaker
Magnesium Orotate recently featured in Readers Digest article Cheaper and Safer Than Prescription Drugs
Magnesium orotate is magnesium salt bound to orotic acid. It’s the most easily absorbed form of magnesium and passes easily through the cells in your body, especially when compared with other types of magnesium. If you need magnesium supplementation, as most people do because the standard American diet often lacks foods high in magnesium, magnesium orotate from Priority One is the most bioavailable Magnesium Orotate on the market get your bottle today!
1 Marz, Russell. Medical Nutrition from Marz. Portland: Omni-Press, 1997.
2 Golf SW, Bender S, Grüttner J. On the significance of magnesium in extreme physical stress. Cardiovasc Drugs Ther. 1998 Sep; 12 Suppl 2:197-202.
3 Stepura OB, Martynow AI. Magnesium orotate in severe congestive heart failure (MACH). Int J Cardiol. 2009 May 1;134(1):145-7.
4 Geiss KR, Stergiou N, Jester, Neuenfeld HU, Jester HG. Effects of magnesium orotate on exercise tolerance in patients with coronary heart disease. Cardiovasc Drugs Ther. 1998 Sep;12 Suppl 2:197-202.
5 Classen, HG. Magnesium orotate–experimental and clinical evidence. Rom J Intern Med. 2004; 42(3):491-501.